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Evaluation of cardiovascular risk assessment models with respect to the clinical interpretation of atherosclerosis in a different type II diabetes cohort

Epidemiological studies on cardiovascular risk developed many assessment models which are widely available for the public use. As many arterial occlusive diseases are developed from atherosclerosis in their early stage, it is meaningful to evaluate such models with respect to the clinical interpreta...

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Autores principales: Chan, L.W.C., Sun, Y.
Formato: Texto
Lenguaje:English
Publicado: American Medical Informatics Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041570/
https://www.ncbi.nlm.nih.gov/pubmed/21347160
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author Chan, L.W.C.
Sun, Y.
author_facet Chan, L.W.C.
Sun, Y.
author_sort Chan, L.W.C.
collection PubMed
description Epidemiological studies on cardiovascular risk developed many assessment models which are widely available for the public use. As many arterial occlusive diseases are developed from atherosclerosis in their early stage, it is meaningful to evaluate such models with respect to the clinical interpretation of atherosclerosis so as to promote the preventive care of vascular diseases. Our study aims to make use of the data collection form from the Hong Kong Chinese type II diabetes to evaluate and compare the performance of the risk assessment models of ARIC, FHS, UKPDS using ROC curve. We found that ARIC’s Stroke model gives the best performance whose AUC is 0.646 in model for Black. UKPDS’s Stroke has the lowest AUC, 0.497. It was found that ARIC model for the Black Americans has superior performance with respect to the cohort in Hong Kong based on the ROC analysis.
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spelling pubmed-30415702011-02-23 Evaluation of cardiovascular risk assessment models with respect to the clinical interpretation of atherosclerosis in a different type II diabetes cohort Chan, L.W.C. Sun, Y. Summit on Translat Bioinforma Articles Epidemiological studies on cardiovascular risk developed many assessment models which are widely available for the public use. As many arterial occlusive diseases are developed from atherosclerosis in their early stage, it is meaningful to evaluate such models with respect to the clinical interpretation of atherosclerosis so as to promote the preventive care of vascular diseases. Our study aims to make use of the data collection form from the Hong Kong Chinese type II diabetes to evaluate and compare the performance of the risk assessment models of ARIC, FHS, UKPDS using ROC curve. We found that ARIC’s Stroke model gives the best performance whose AUC is 0.646 in model for Black. UKPDS’s Stroke has the lowest AUC, 0.497. It was found that ARIC model for the Black Americans has superior performance with respect to the cohort in Hong Kong based on the ROC analysis. American Medical Informatics Association 2009-03-01 /pmc/articles/PMC3041570/ /pubmed/21347160 Text en ©2009 AMIA - All rights reserved. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose
spellingShingle Articles
Chan, L.W.C.
Sun, Y.
Evaluation of cardiovascular risk assessment models with respect to the clinical interpretation of atherosclerosis in a different type II diabetes cohort
title Evaluation of cardiovascular risk assessment models with respect to the clinical interpretation of atherosclerosis in a different type II diabetes cohort
title_full Evaluation of cardiovascular risk assessment models with respect to the clinical interpretation of atherosclerosis in a different type II diabetes cohort
title_fullStr Evaluation of cardiovascular risk assessment models with respect to the clinical interpretation of atherosclerosis in a different type II diabetes cohort
title_full_unstemmed Evaluation of cardiovascular risk assessment models with respect to the clinical interpretation of atherosclerosis in a different type II diabetes cohort
title_short Evaluation of cardiovascular risk assessment models with respect to the clinical interpretation of atherosclerosis in a different type II diabetes cohort
title_sort evaluation of cardiovascular risk assessment models with respect to the clinical interpretation of atherosclerosis in a different type ii diabetes cohort
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041570/
https://www.ncbi.nlm.nih.gov/pubmed/21347160
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