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Deep RNA sequencing analysis of readthrough gene fusions in human prostate adenocarcinoma and reference samples

BACKGROUND: Readthrough fusions across adjacent genes in the genome, or transcription-induced chimeras (TICs), have been estimated using expressed sequence tag (EST) libraries to involve 4-6% of all genes. Deep transcriptional sequencing (RNA-Seq) now makes it possible to study the occurrence and ex...

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Detalles Bibliográficos
Autores principales: Nacu, Serban, Yuan, Wenlin, Kan, Zhengyan, Bhatt, Deepali, Rivers, Celina Sanchez, Stinson, Jeremy, Peters, Brock A, Modrusan, Zora, Jung, Kenneth, Seshagiri, Somasekar, Wu, Thomas D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041646/
https://www.ncbi.nlm.nih.gov/pubmed/21261984
http://dx.doi.org/10.1186/1755-8794-4-11

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