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Intensified treatment with high dose Rifampicin and Levofloxacin compared to standard treatment for adult patients with Tuberculous Meningitis (TBM-IT): protocol for a randomized controlled trial

BACKGROUND: Tuberculous meningitis is the most severe form of tuberculosis. Mortality for untreated tuberculous meningitis is 100%. Despite the introduction of antibiotic treatment for tuberculosis the mortality rate for tuberculous meningitis remains high; approximately 25% for HIV-negative and 67%...

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Detalles Bibliográficos
Autores principales: Heemskerk, Dorothee, Day, Jeremy, Chau, Tran Thi Hong, Dung, Nguyen Huy, Yen, Nguyen Thi Bich, Bang, Nguyen Duc, Merson, Laura, Olliaro, Piero, Pouplin, Thomas, Caws, Maxine, Wolbers, Marcel, Farrar, Jeremy
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041687/
https://www.ncbi.nlm.nih.gov/pubmed/21288325
http://dx.doi.org/10.1186/1745-6215-12-25