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Neurotensin Receptor 1 Is Expressed in Gastrointestinal Stromal Tumors but Not in Interstitial Cells of Cajal

Gastrointestinal stromal tumors (GIST) are thought to derive from the interstitial cells of Cajal (ICC) or an ICC precursor. Oncogenic mutations of the KIT or PDGFRA receptor tyrosine kinases are present in the majority of GIST, leading to ligand-independent activation of the intracellular signal tr...

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Detalles Bibliográficos
Autores principales: Gromova, Petra, Rubin, Brian P., Thys, An, Erneux, Christophe, Vanderwinden, Jean-Marie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041753/
https://www.ncbi.nlm.nih.gov/pubmed/21364741
http://dx.doi.org/10.1371/journal.pone.0014710