Cargando…
Neurotensin Receptor 1 Is Expressed in Gastrointestinal Stromal Tumors but Not in Interstitial Cells of Cajal
Gastrointestinal stromal tumors (GIST) are thought to derive from the interstitial cells of Cajal (ICC) or an ICC precursor. Oncogenic mutations of the KIT or PDGFRA receptor tyrosine kinases are present in the majority of GIST, leading to ligand-independent activation of the intracellular signal tr...
Autores principales: | Gromova, Petra, Rubin, Brian P., Thys, An, Erneux, Christophe, Vanderwinden, Jean-Marie |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041753/ https://www.ncbi.nlm.nih.gov/pubmed/21364741 http://dx.doi.org/10.1371/journal.pone.0014710 |
Ejemplares similares
-
Kit K641E oncogene up-regulates Sprouty homolog 4 and Trophoblast glycoprotein in interstitial cells of Cajal in a murine model of gastrointestinal stromal tumours
por: Gromova, Petra, et al.
Publicado: (2009) -
ENDOGLIN/CD105 is expressed in KIT positive cells in the gut and in gastrointestinal stromal tumours
por: Gromova, Petra, et al.
Publicado: (2012) -
Hyperplasia of Interstitial Cells of Cajal in Sprouty Homolog 4 Deficient Mice
por: Thys, An, et al.
Publicado: (2015) -
Phosphodiesterase 3A: a new player in development of interstitial cells of Cajal and a prospective target in gastrointestinal stromal tumors (GIST)
por: Vandenberghe, Pierre, et al.
Publicado: (2017) -
Potentiation of imatinib by cilostazol in sensitive and resistant gastrointestinal stromal tumor cell lines involves YAP inhibition
por: Vandenberghe, Pierre, et al.
Publicado: (2019)