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The porcine circovirus type 1 capsid gene promoter improves antigen expression and immunogenicity in a HIV-1 plasmid vaccine

BACKGROUND: One of the promising avenues for development of vaccines against Human immunodeficiency virus type 1 (HIV-1) and other human pathogens is the use of plasmid-based DNA vaccines. However, relatively large doses of plasmid must be injected for a relatively weak response. We investigated whe...

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Detalles Bibliográficos
Autores principales: Tanzer, Fiona L, Shephard, Enid G, Palmer, Kenneth E, Burger, Marieta, Williamson, Anna-Lise, Rybicki, Edward P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041773/
https://www.ncbi.nlm.nih.gov/pubmed/21299896
http://dx.doi.org/10.1186/1743-422X-8-51