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The porcine circovirus type 1 capsid gene promoter improves antigen expression and immunogenicity in a HIV-1 plasmid vaccine
BACKGROUND: One of the promising avenues for development of vaccines against Human immunodeficiency virus type 1 (HIV-1) and other human pathogens is the use of plasmid-based DNA vaccines. However, relatively large doses of plasmid must be injected for a relatively weak response. We investigated whe...
Autores principales: | Tanzer, Fiona L, Shephard, Enid G, Palmer, Kenneth E, Burger, Marieta, Williamson, Anna-Lise, Rybicki, Edward P |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041773/ https://www.ncbi.nlm.nih.gov/pubmed/21299896 http://dx.doi.org/10.1186/1743-422X-8-51 |
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