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SFRP1 reduction results in an increased sensitivity to TGF-β signaling

BACKGROUND: Transforming growth factor (TGF)-β plays a dual role during mammary gland development and tumorigenesis and has been shown to stimulate epithelial-mesenchymal transition (EMT) as well as cellular migration. The Wnt/β-catenin pathway is also implicated in EMT and inappropriate activation...

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Detalles Bibliográficos
Autores principales:	Gauger, Kelly J, Chenausky, Kerry L, Murray, Molly E, Schneider, Sallie S
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041779/ https://www.ncbi.nlm.nih.gov/pubmed/21303533 http://dx.doi.org/10.1186/1471-2407-11-59

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