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Retroperitoneal Metastatic Adenocarcinoma Complicated with Necrotizing Fasciitis of the Thigh in a Patient with Advanced Rectal Colon Cancer
BACKGROUND: Necrotizing fasciitis of the thigh due to colon cancer has not been previously reported, especially during radiotherapy. CASE PRESENTATION: A 73-year-old woman admitted to our hospital was diagnosed with sigmoid colon cancer that had spread to the left psoas muscle; radiotherapy was perf...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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S. Karger AG
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042024/ https://www.ncbi.nlm.nih.gov/pubmed/21347198 http://dx.doi.org/10.1159/000319829 |
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author | Chen, Jia-Hong Chang, Ping-Ying Ho, Ching-Liang Chen, Yeu-Chin Kao, Wei-Yau |
author_facet | Chen, Jia-Hong Chang, Ping-Ying Ho, Ching-Liang Chen, Yeu-Chin Kao, Wei-Yau |
author_sort | Chen, Jia-Hong |
collection | PubMed |
description | BACKGROUND: Necrotizing fasciitis of the thigh due to colon cancer has not been previously reported, especially during radiotherapy. CASE PRESENTATION: A 73-year-old woman admitted to our hospital was diagnosed with sigmoid colon cancer that had spread to the left psoas muscle; radiotherapy was performed. Three months after the initiation of radiotherapy, the patient developed gait disturbance, poor appetite and high fever and was therefore admitted to the emergency department of our hospital. Blood examination revealed generalized inflammation with a high white blood cell count and C-reactive protein level. Computed tomography of the abdomen revealed fluid and gas tracking from the retroperitoneum into the intramuscular plane of the grossly enlarged right thigh. Consequently, emergent debridement was not performed and conservative therapy was done. The patient died. CONCLUSION: Necrotizing fasciitis of the thigh due to the spread of rectal colon cancer is unusual, but this fatal complication should be considered during radiotherapy in patients with unresectable colorectal cancer. |
format | Text |
id | pubmed-3042024 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-30420242011-02-23 Retroperitoneal Metastatic Adenocarcinoma Complicated with Necrotizing Fasciitis of the Thigh in a Patient with Advanced Rectal Colon Cancer Chen, Jia-Hong Chang, Ping-Ying Ho, Ching-Liang Chen, Yeu-Chin Kao, Wei-Yau Case Rep Oncol Published: August 2010 BACKGROUND: Necrotizing fasciitis of the thigh due to colon cancer has not been previously reported, especially during radiotherapy. CASE PRESENTATION: A 73-year-old woman admitted to our hospital was diagnosed with sigmoid colon cancer that had spread to the left psoas muscle; radiotherapy was performed. Three months after the initiation of radiotherapy, the patient developed gait disturbance, poor appetite and high fever and was therefore admitted to the emergency department of our hospital. Blood examination revealed generalized inflammation with a high white blood cell count and C-reactive protein level. Computed tomography of the abdomen revealed fluid and gas tracking from the retroperitoneum into the intramuscular plane of the grossly enlarged right thigh. Consequently, emergent debridement was not performed and conservative therapy was done. The patient died. CONCLUSION: Necrotizing fasciitis of the thigh due to the spread of rectal colon cancer is unusual, but this fatal complication should be considered during radiotherapy in patients with unresectable colorectal cancer. S. Karger AG 2010-08-12 /pmc/articles/PMC3042024/ /pubmed/21347198 http://dx.doi.org/10.1159/000319829 Text en Copyright © 2010 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published: August 2010 Chen, Jia-Hong Chang, Ping-Ying Ho, Ching-Liang Chen, Yeu-Chin Kao, Wei-Yau Retroperitoneal Metastatic Adenocarcinoma Complicated with Necrotizing Fasciitis of the Thigh in a Patient with Advanced Rectal Colon Cancer |
title | Retroperitoneal Metastatic Adenocarcinoma Complicated with Necrotizing Fasciitis of the Thigh in a Patient with Advanced Rectal Colon Cancer |
title_full | Retroperitoneal Metastatic Adenocarcinoma Complicated with Necrotizing Fasciitis of the Thigh in a Patient with Advanced Rectal Colon Cancer |
title_fullStr | Retroperitoneal Metastatic Adenocarcinoma Complicated with Necrotizing Fasciitis of the Thigh in a Patient with Advanced Rectal Colon Cancer |
title_full_unstemmed | Retroperitoneal Metastatic Adenocarcinoma Complicated with Necrotizing Fasciitis of the Thigh in a Patient with Advanced Rectal Colon Cancer |
title_short | Retroperitoneal Metastatic Adenocarcinoma Complicated with Necrotizing Fasciitis of the Thigh in a Patient with Advanced Rectal Colon Cancer |
title_sort | retroperitoneal metastatic adenocarcinoma complicated with necrotizing fasciitis of the thigh in a patient with advanced rectal colon cancer |
topic | Published: August 2010 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042024/ https://www.ncbi.nlm.nih.gov/pubmed/21347198 http://dx.doi.org/10.1159/000319829 |
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