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The significance of the complement system for the pathogenesis of age-related macular degeneration — current evidence and translation into clinical application

BACKGROUND: Dysregulation of the complement system has been shown to play a major role in the pathogenesis of age-related macular degeneration (AMD). METHODS: The current evidence from human studies derives from immunohistochemical and proteomic studies in donor eyes, genetic association studies, an...

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Detalles Bibliográficos
Autores principales: Charbel Issa, Peter, Victor Chong, N., Scholl, Hendrik P. N.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042099/
https://www.ncbi.nlm.nih.gov/pubmed/21127893
http://dx.doi.org/10.1007/s00417-010-1568-6