AGE: defining breakpoints of genomic structural variants at single-nucleotide resolution, through optimal alignments with gap excision

Motivation: Defining the precise location of structural variations (SVs) at single-nucleotide breakpoint resolution is an important problem, as it is a prerequisite for classifying SVs, evaluating their functional impact and reconstructing personal genome sequences. Given approximate breakpoint loca...

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Detalles Bibliográficos
Autores principales: Abyzov, Alexej, Gerstein, Mark
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042181/
https://www.ncbi.nlm.nih.gov/pubmed/21233167
http://dx.doi.org/10.1093/bioinformatics/btq713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042181/
https://www.ncbi.nlm.nih.gov/pubmed/21233167
http://dx.doi.org/10.1093/bioinformatics/btq713

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