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An update on targeted gene repair in mammalian cells: methods and mechanisms

Transfer of full-length genes including regulatory elements has been the preferred gene therapy strategy for clinical applications. However, with significant drawbacks emerging, targeted gene alteration (TGA) has recently become a promising alternative to this method. By means of TGA, endogenous DNA...

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Detalles Bibliográficos
Autores principales:	Jensen, Nanna M, Dalsgaard, Trine, Jakobsen, Maria, Nielsen, Roni R, Sørensen, Charlotte B, Bolund, Lars, Jensen, Thomas G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042377/ https://www.ncbi.nlm.nih.gov/pubmed/21284895 http://dx.doi.org/10.1186/1423-0127-18-10

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