The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species

BACKGROUND: The farnesoid X receptor (FXR), pregnane X receptor (PXR), and vitamin D receptor (VDR) are three closely related nuclear hormone receptors in the NR1H and 1I subfamilies that share the property of being activated by bile salts. Bile salts vary significantly in structure across vertebrat...

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Detalles Bibliográficos
Autores principales: Krasowski, Matthew D, Ai, Ni, Hagey, Lee R, Kollitz, Erin M, Kullman, Seth W, Reschly, Erica J, Ekins, Sean
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042382/
https://www.ncbi.nlm.nih.gov/pubmed/21291553
http://dx.doi.org/10.1186/1471-2091-12-5

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