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Effects of EpCAM overexpression on human breast cancer cell lines

BACKGROUND: Recently, EpCAM has attracted major interest as a target for antibody- and vaccine-based cancer immunotherapies. In breast cancer, the EpCAM antigen is overexpressed in 30-40% of all cases and this increased expression correlates with poor prognosis. The use of EpCAM-specific monoclonal...

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Detalles Bibliográficos
Autores principales: Gostner, Johanna M, Fong, Dominic, Wrulich, Oliver A, Lehne, Florian, Zitt, Marion, Hermann, Martin, Krobitsch, Sylvia, Martowicz, Agnieszka, Gastl, Guenther, Spizzo, Gilbert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042418/
https://www.ncbi.nlm.nih.gov/pubmed/21281469
http://dx.doi.org/10.1186/1471-2407-11-45