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Inositol-requiring 1/X-box-binding protein 1 is a regulatory hub that links endoplasmic reticulum homeostasis with innate immunity and metabolism
Inositol-requiring 1 (IRE1)/X-box-binding protein 1 (XBP1)-mediated signalling represents the most conserved branch of the unfolded protein response. A series of recent studies reveal novel and potentially ancient roles for this pathway in the coordination of metabolic and immune responses.
Autores principales: | Kaufman, Randal J, Cao, Siyan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042734/ https://www.ncbi.nlm.nih.gov/pubmed/20533428 http://dx.doi.org/10.1002/emmm.201000076 |
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