Cargando…

Identification of a Chemical That Inhibits the Mycobacterial UvrABC Complex in Nucleotide Excision Repair

[Image: see text] Bacterial DNA can be damaged by reactive nitrogen and oxygen intermediates (RNI and ROI) generated by host immunity, as well as by antibiotics that trigger bacterial production of ROI. Thus a pathogen’s ability to repair its DNA may be important for persistent infection. A prominen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mazloum, Nayef, Stegman, Melanie A., Croteau, Deborah L., Van Houten, Bennett, Kwon, Nyoun Soo, Ling, Yan, Dickinson, Caitlyn, Venugopal, Aditya, Towheed, Mohammad Atif, Nathan, Carl
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2011
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042777/ https://www.ncbi.nlm.nih.gov/pubmed/21235228 http://dx.doi.org/10.1021/bi101674c

Ejemplares similares

Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease
por: Christensen, Laura A., et al.
Publicado: (2008)

Repair of mitomycin C mono- and interstrand cross-linked DNA adducts by UvrABC: a new model
por: Weng, Mao-wen, et al.
Publicado: (2010)

Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes
por: Hughes, Craig D., et al.
Publicado: (2013)

The unstructured C-terminal extension of UvrD interacts with UvrB, but is dispensable for nucleotide excision repair
por: Manelyte, Laura, et al.
Publicado: (2009)

Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System
por: Lee, Seung-Joo, et al.
Publicado: (2019)

Crystal Structure of the FeS Cluster–Containing Nucleotide Excision Repair Helicase XPD
por: Wolski, Stefanie C, et al.
Publicado: (2008)

Recruitment of UvrBC complexes to UV-induced damage in the absence of UvrA increases cell survival
por: Springall, Luke, et al.
Publicado: (2018)

Investigation of bacterial nucleotide excision repair using single-molecule techniques
por: Van Houten, Bennett, et al.
Publicado: (2014)

The involvement of nucleotide excision repair proteins in the removal of oxidative DNA damage
por: Kumar, Namrata, et al.
Publicado: (2020)

The ATPase mechanism of UvrA(2) reveals the distinct roles of proximal and distal ATPase sites in nucleotide excision repair
por: Case, Brandon C, et al.
Publicado: (2019)

UvrD Participation in Nucleotide Excision Repair Is Required for the Recovery of DNA Synthesis following UV-Induced Damage in Escherichia coli
por: Newton, Kelley N., et al.
Publicado: (2012)

Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans
por: Meyer, Joel N, et al.
Publicado: (2007)

Chaperones for dancing on chromatin: Role of post-translational modifications in dynamic damage detection hand-offs during nucleotide excision repair
por: Van Houten, Bennett, et al.
Publicado: (2021)

Cooperation and interplay between base and nucleotide excision repair pathways: From DNA lesions to proteins
por: Kumar, Namrata, et al.
Publicado: (2020)

Removal of Misincorporated Ribonucleotides from Prokaryotic Genomes: An Unexpected Role for Nucleotide Excision Repair
por: Vaisman, Alexandra, et al.
Publicado: (2013)

{OElig}uvres
por: Rimbaud, Arthur, 1854-1891
Publicado: (1950)

Repair activity of base and nucleotide excision repair enzymes for guanine lesions induced by nitrosative stress
por: Nakano, Toshiaki, et al.
Publicado: (2005)

Crystal structure of the UvrB dimer: insights into the nature and functioning of the UvrAB damage engagement and UvrB–DNA complexes
por: Webster, Matthew P. J., et al.
Publicado: (2012)

{OElig}uvres complétes
por: Lamartine, Alphonse de, 1790-1869
Publicado: (1834)

{OElig}uvres chorales
por: Brossard, Sébastien de, d. 1730
Publicado: (1997)

{OElig}uvres complétes
por: Barraqué, Jean
Publicado: (1998)

{OElig}uvres complétes /
por: Pascal, Blaise, 1623-1662
Publicado: (1998)

{OElig}uvres complétes /
por: Lautréamont, conde de, 1846-1870
Publicado: (1970)

{OElig}uvres complétes /
por: Nerval, Gérard de, 1808-1855
Publicado: (1989)

L'{oelig}uvre /
por: Zola, Émile, 1840-1902
Publicado: (1983)

{OElig}uvres complétes
por: Domenichino, 1581-1641
Publicado: (1864)

The ABC exporter IrtAB imports and reduces mycobacterial siderophores
por: Arnold, Fabian M., et al.
Publicado: (2020)

The uvrA, uvrB and uvrC genes are required for repair of ultraviolet light induced DNA photoproducts in Halobacterium sp. NRC-1
por: Crowley, David J, et al.
Publicado: (2006)

Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase β
por: Asagoshi, Kenjiro, et al.
Publicado: (2012)

Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins
por: Kumar, Namrata, et al.
Publicado: (2022)

{OElig}uvres pour 2 pianos {OElig}uvres pour piano /
por: Poulenc, Francis, 1899-1963
Publicado: (1991)

{OElig}uvres romanesques complétes /
por: Aragon, 1897-
Publicado: (1997)

{OElig}uvres poétiques complétes /
por: Supervielle, Jules, 1884-1960
Publicado: (1996)

Oe{OElig}uvres complétes /
por: Mallarmé, Stéphane, 1842-1898
Publicado: (1989)

{OElig}uvres poétiques complétes /
por: Verlaine, Paul, 1844-1896
Publicado: (1992)

Nucleotide excision repair: a versatile and smart toolkit: Nucleotide excision repair
por: Zhang, Xiping, et al.
Publicado: (2022)

Nucleotide Excision Repair in Cellular Chromatin: Studies with Yeast from Nucleotide to Gene to Genome
por: Waters, Raymond, et al.
Publicado: (2012)

Directly interrogating single quantum dot labelled UvrA(2) molecules on DNA tightropes using an optically trapped nanoprobe
por: Simons, Michelle, et al.
Publicado: (2015)

Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
por: Stracy, Mathew, et al.
Publicado: (2016)

UvrD helicase–RNA polymerase interactions are governed by UvrD’s carboxy-terminal Tudor domain
por: Kawale, Ashish A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_tl1ccv2ol8nbh93ftgf5beprft