Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones

The neuropeptide substance-P (SP) is expressed from the TAC1 gene in sensory neurones where it acts as a key modulator of neurogenic inflammation. The promoter of TAC1 (TAC1prom) plays a central role in the regulation of the TAC1 gene but requires the presence of a second regulatory element; ECR2, t...

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Detalles Bibliográficos
Autores principales: Shanley, Lynne, Lear, Marissa, Davidson, Scott, Ross, Ruth, MacKenzie, Alasdair
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042928/
https://www.ncbi.nlm.nih.gov/pubmed/21294877
http://dx.doi.org/10.1186/1742-2094-8-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042928/
https://www.ncbi.nlm.nih.gov/pubmed/21294877
http://dx.doi.org/10.1186/1742-2094-8-10

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