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Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones
The neuropeptide substance-P (SP) is expressed from the TAC1 gene in sensory neurones where it acts as a key modulator of neurogenic inflammation. The promoter of TAC1 (TAC1prom) plays a central role in the regulation of the TAC1 gene but requires the presence of a second regulatory element; ECR2, t...
Autores principales: | Shanley, Lynne, Lear, Marissa, Davidson, Scott, Ross, Ruth, MacKenzie, Alasdair |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042928/ https://www.ncbi.nlm.nih.gov/pubmed/21294877 http://dx.doi.org/10.1186/1742-2094-8-10 |
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