A novel HPV 16 L1-based chimeric virus-like particle containing E6 and E7 seroreactive epitopes permits highly specific detection of antibodies in patients with CIN 1 and HPV-16 infection

BACKGROUND: The presence of IgG antibodies to HPV-16 L1-virus like particles (VLPs) in serum has been reported as a result of persistent exposure to the virus and as a marker of disease progression. However, detection of VLP-specific antibodies in sera does not always indicate a malignant lesion as...

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Detalles Bibliográficos
Autores principales: Monroy-García, Alberto, Gómez-Lim, Miguel A, Weiss-Steider, Benny, la Rosa, Georgina Paz-de, Hernández-Montes, Jorge, Pérez-Saldaña, Karyna, Tapia-Guerrero, Yessica S, Toledo-Guzmán, Mariel E, Santiago-Osorio, Edelmiro, Sanchez-Peña, Héctor I, Mora-García, María de Lourdes
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042957/
https://www.ncbi.nlm.nih.gov/pubmed/21306638
http://dx.doi.org/10.1186/1743-422X-8-59

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