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In vivo Identification and Specificity assessment of mRNA markers of hypoxia in human and mouse tumors
BACKGROUND: Tumor hypoxia is linked to poor prognosis, but identification and quantification of tissue hypoxia remains a challenge. The hypoxia-specificity of HIF-1α target genes in vivo has been questioned due to the confounding influence of other microenvironmental abnormalities known to affect ge...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042974/ https://www.ncbi.nlm.nih.gov/pubmed/21306648 http://dx.doi.org/10.1186/1471-2407-11-63 |