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Identifying Consensus Disease Pathways in Parkinson's Disease Using an Integrative Systems Biology Approach

Parkinson's disease (PD) has had six genome-wide association studies (GWAS) conducted as well as several gene expression studies. However, only variants in MAPT and SNCA have been consistently replicated. To improve the utility of these approaches, we applied pathway analyses integrating both G...

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Detalles Bibliográficos
Autores principales: Edwards, Yvonne J. K., Beecham, Gary W., Scott, William K., Khuri, Sawsan, Bademci, Guney, Tekin, Demet, Martin, Eden R., Jiang, Zhijie, Mash, Deborah C., ffrench-Mullen, Jarlath, Pericak-Vance, Margaret A., Tsinoremas, Nicholas, Vance, Jeffery M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043094/
https://www.ncbi.nlm.nih.gov/pubmed/21364952
http://dx.doi.org/10.1371/journal.pone.0016917