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Plasmin Inhibitors Prevent Leukocyte Accumulation and Remodeling Events in the Postischemic Microvasculature
Clinical trials revealed beneficial effects of the broad-spectrum serine protease inhibitor aprotinin on the prevention of ischemia-reperfusion (I/R) injury. The underlying mechanisms remained largely unclear. Using in vivo microscopy on the cremaster muscle of male C57BL/6 mice, aprotinin as well a...
Autores principales: | Reichel, Christoph A., Lerchenberger, Max, Uhl, Bernd, Rehberg, Markus, Berberich, Nina, Zahler, Stefan, Wymann, Matthias P., Krombach, Fritz |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043096/ https://www.ncbi.nlm.nih.gov/pubmed/21364954 http://dx.doi.org/10.1371/journal.pone.0017229 |
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