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Metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency: implications for the pathogenesis of steatohepatitis

The pathological mechanisms that distinguish simple steatosis from steatohepatitis (or NASH, with consequent risk of cirrhosis and hepatocellular cancer) remain incompletely defined. Whereas both a methionine- and choline-deficient diet (MCDD) and a choline-deficient diet (CDD) lead to hepatic trigl...

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Detalles Bibliográficos
Autores principales:	Macfarlane, David P., Zou, Xiantong, Andrew, Ruth, Morton, Nicholas M., Livingstone, Dawn E. W., Aucott, Rebecca L., Nyirenda, Moffat J., Iredale, John P., Walker, Brian R.
Formato:	Texto
Lenguaje:	English
Publicado:	American Physiological Society 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043621/ https://www.ncbi.nlm.nih.gov/pubmed/21119028 http://dx.doi.org/10.1152/ajpendo.00331.2010

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