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Convection and Retro-Convection Enhanced Delivery: Some Theoretical Considerations Related to Drug Targeting

Delivery of drugs and macromolecules into the brain is a challenging problem, due in part to the blood–brain barrier. In this article, we focus on the possibilities and limitations of two infusion techniques devised to bypass the blood–brain barrier: convection enhanced delivery (CED) and retro-conv...

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Detalles Bibliográficos
Autores principales: Motion, J. P. Michael, Huynh, Grace H., Szoka, Francis C., Siegel, Ronald A.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044083/
https://www.ncbi.nlm.nih.gov/pubmed/20963628
http://dx.doi.org/10.1007/s11095-010-0296-2