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Convection and Retro-Convection Enhanced Delivery: Some Theoretical Considerations Related to Drug Targeting
Delivery of drugs and macromolecules into the brain is a challenging problem, due in part to the blood–brain barrier. In this article, we focus on the possibilities and limitations of two infusion techniques devised to bypass the blood–brain barrier: convection enhanced delivery (CED) and retro-conv...
Autores principales: | Motion, J. P. Michael, Huynh, Grace H., Szoka, Francis C., Siegel, Ronald A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044083/ https://www.ncbi.nlm.nih.gov/pubmed/20963628 http://dx.doi.org/10.1007/s11095-010-0296-2 |
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