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In Vivo Methods to Study Uptake of Nanoparticles into the Brain
Several in vivo techniques have been developed to study and measure the uptake of CNS compounds into the brain. With these techniques, various parameters can be determined after drug administration, including the blood-to-brain influx constant (K(in)), the permeability-surface area (PS) product, and...
Autores principales: | van Rooy, Inge, Cakir-Tascioglu, Serpil, Hennink, Wim E., Storm, Gert, Schiffelers, Raymond M., Mastrobattista, Enrico |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044085/ https://www.ncbi.nlm.nih.gov/pubmed/20924653 http://dx.doi.org/10.1007/s11095-010-0291-7 |
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