Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome

Autophagy protects organelles, cells, and organisms against several stress conditions. Induction of autophagy by resveratrol requires the nicotinamide adenine dinucleotide–dependent deacetylase sirtuin 1 (SIRT1). In this paper, we show that the acetylase inhibitor spermidine stimulates autophagy ind...

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Detalles Bibliográficos
Autores principales: Morselli, Eugenia, Mariño, Guillermo, Bennetzen, Martin V., Eisenberg, Tobias, Megalou, Evgenia, Schroeder, Sabrina, Cabrera, Sandra, Bénit, Paule, Rustin, Pierre, Criollo, Alfredo, Kepp, Oliver, Galluzzi, Lorenzo, Shen, Shensi, Malik, Shoaib Ahmad, Maiuri, Maria Chiara, Horio, Yoshiyuki, López-Otín, Carlos, Andersen, Jens S., Tavernarakis, Nektarios, Madeo, Frank, Kroemer, Guido
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044119/
https://www.ncbi.nlm.nih.gov/pubmed/21339330
http://dx.doi.org/10.1083/jcb.201008167

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