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Polycystin-2 takes different routes to the somatic and ciliary plasma membrane

Polycystin-2 (also called TRPP2), an integral membrane protein mutated in patients with cystic kidney disease, is located in the primary cilium where it is thought to transmit mechanical stimuli into the cell interior. After studying a series of polycystin-2 deletion mutants we identified two amino...

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Detalles Bibliográficos
Autores principales: Hoffmeister, Helen, Babinger, Karin, Gürster, Sonja, Cedzich, Anna, Meese, Christine, Schadendorf, Karin, Osten, Larissa, de Vries, Uwe, Rascle, Anne, Witzgall, Ralph
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044124/
https://www.ncbi.nlm.nih.gov/pubmed/21321097
http://dx.doi.org/10.1083/jcb.201007050

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