Centrosome docking at the immunological synapse is controlled by Lck signaling

Docking of the centrosome at the plasma membrane directs lytic granules to the immunological synapse. To identify signals controlling centrosome docking at the synapse, we have studied cytotoxic T lymphocytes (CTLs) in which expression of the T cell receptor–activated tyrosine kinase Lck is ablated....

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Detalles Bibliográficos
Autores principales: Tsun, Andy, Qureshi, Ihjaaz, Stinchcombe, Jane C., Jenkins, Misty R., de la Roche, Maike, Kleczkowska, Joanna, Zamoyska, Rose, Griffiths, Gillian M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044125/
https://www.ncbi.nlm.nih.gov/pubmed/21339332
http://dx.doi.org/10.1083/jcb.201008140

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