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Activation of Peroxisome Proliferator-Activated Receptor Gamma by Rosiglitazone Increases Sirt6 Expression and Ameliorates Hepatic Steatosis in Rats
BACKGROUND: Sirt6 has been implicated in the regulation of hepatic lipid metabolism and the development of hepatic steatosis. The aim of this study was to address the potential role of Sirt6 in the protective effects of rosiglitazone (RGZ) on hepatic steatosis. METHODS: To investigate the effect of...
Autores principales: | Yang, Soo Jin, Choi, Jung Mook, Chae, Seoung Wan, Kim, Won Jun, Park, Se Eun, Rhee, Eun Jung, Lee, Won Young, Oh, Ki Won, Park, Sung Woo, Kim, Sun Woo, Park, Cheol-Young |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044155/ https://www.ncbi.nlm.nih.gov/pubmed/21373642 http://dx.doi.org/10.1371/journal.pone.0017057 |
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