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Modeling allosteric signal propagation using protein structure networks

Allosteric communication in proteins can be induced by the binding of effective ligands, mutations or covalent modifications that regulate a site distant from the perturbed region. To understand allosteric regulation, it is important to identify the remote sites that are affected by the perturbation...

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Detalles Bibliográficos
Autores principales: Park, Keunwan, Kim, Dongsup
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044278/
https://www.ncbi.nlm.nih.gov/pubmed/21342553
http://dx.doi.org/10.1186/1471-2105-12-S1-S23