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Changed epitopes drive the antigenic drift for influenza A (H3N2) viruses
BACKGROUND: In circulating influenza viruses, gradually accumulated mutations on the glycoprotein hemagglutinin (HA), which interacts with infectivity-neutralizing antibodies, lead to the escape of immune system (called antigenic drift). The antibody recognition is highly correlated to the conformat...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044287/ https://www.ncbi.nlm.nih.gov/pubmed/21342562 http://dx.doi.org/10.1186/1471-2105-12-S1-S31 |