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Changed epitopes drive the antigenic drift for influenza A (H3N2) viruses

BACKGROUND: In circulating influenza viruses, gradually accumulated mutations on the glycoprotein hemagglutinin (HA), which interacts with infectivity-neutralizing antibodies, lead to the escape of immune system (called antigenic drift). The antibody recognition is highly correlated to the conformat...

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Detalles Bibliográficos
Autores principales:	Huang, Jhang-Wei, Yang, Jinn-Moon
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044287/ https://www.ncbi.nlm.nih.gov/pubmed/21342562 http://dx.doi.org/10.1186/1471-2105-12-S1-S31

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