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Production of Lantipeptides in Escherichia coli

[Image: see text] Lantipeptides are ribosomally synthesized and posttranslationally modified peptides containing thioether cross-links. We describe the preparation of seven different lantipeptides in Escherichia coli and demonstrate that this methodology can be used to incorporate nonproteinogenic a...

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Detalles Bibliográficos
Autores principales: Shi, Yanxiang, Yang, Xiao, Garg, Neha, van der Donk, Wilfred A.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044485/
https://www.ncbi.nlm.nih.gov/pubmed/21114289
http://dx.doi.org/10.1021/ja109044r
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author Shi, Yanxiang
Yang, Xiao
Garg, Neha
van der Donk, Wilfred A.
author_facet Shi, Yanxiang
Yang, Xiao
Garg, Neha
van der Donk, Wilfred A.
author_sort Shi, Yanxiang
collection PubMed
description [Image: see text] Lantipeptides are ribosomally synthesized and posttranslationally modified peptides containing thioether cross-links. We describe the preparation of seven different lantipeptides in Escherichia coli and demonstrate that this methodology can be used to incorporate nonproteinogenic amino acids.
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spelling pubmed-30444852011-02-24 Production of Lantipeptides in Escherichia coli Shi, Yanxiang Yang, Xiao Garg, Neha van der Donk, Wilfred A. J Am Chem Soc [Image: see text] Lantipeptides are ribosomally synthesized and posttranslationally modified peptides containing thioether cross-links. We describe the preparation of seven different lantipeptides in Escherichia coli and demonstrate that this methodology can be used to incorporate nonproteinogenic amino acids. American Chemical Society 2010-11-29 2011-03-02 /pmc/articles/PMC3044485/ /pubmed/21114289 http://dx.doi.org/10.1021/ja109044r Text en Copyright © 2010 American Chemical Society http://pubs.acs.org This is an open-access article distributed under the ACS AuthorChoice Terms & Conditions. Any use of this article, must conform to the terms of that license which are available at http://pubs.acs.org.
spellingShingle Shi, Yanxiang
Yang, Xiao
Garg, Neha
van der Donk, Wilfred A.
Production of Lantipeptides in Escherichia coli
title Production of Lantipeptides in Escherichia coli
title_full Production of Lantipeptides in Escherichia coli
title_fullStr Production of Lantipeptides in Escherichia coli
title_full_unstemmed Production of Lantipeptides in Escherichia coli
title_short Production of Lantipeptides in Escherichia coli
title_sort production of lantipeptides in escherichia coli
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044485/
https://www.ncbi.nlm.nih.gov/pubmed/21114289
http://dx.doi.org/10.1021/ja109044r
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AT gargneha productionoflantipeptidesinescherichiacoli
AT vanderdonkwilfreda productionoflantipeptidesinescherichiacoli