CTX-M β-Lactamase Production and Virulence of Escherichia coli K1

We report a patient with neonatal meningitis caused by a CTX-M-1–producing Escherichia coli K1 strain. The influence of CTX-M production on virulence was investigated in cell culture and a newborn mouse model of meningitis. CTX-M production had no influence on virulence but was a major factor in cli...

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Detalles Bibliográficos
Autores principales: Dubois, Damien, Prasadarao, Nemani V., Mittal, Rahul, Bret, Laurent, Roujou-Gris, Marie, Bonnet, Richard
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2009
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044546/
https://www.ncbi.nlm.nih.gov/pubmed/19961682
http://dx.doi.org/10.3201/eid1512.090928
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author Dubois, Damien
Prasadarao, Nemani V.
Mittal, Rahul
Bret, Laurent
Roujou-Gris, Marie
Bonnet, Richard
author_facet Dubois, Damien
Prasadarao, Nemani V.
Mittal, Rahul
Bret, Laurent
Roujou-Gris, Marie
Bonnet, Richard
author_sort Dubois, Damien
collection PubMed
description We report a patient with neonatal meningitis caused by a CTX-M-1–producing Escherichia coli K1 strain. The influence of CTX-M production on virulence was investigated in cell culture and a newborn mouse model of meningitis. CTX-M production had no influence on virulence but was a major factor in clinical outcome.
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spelling pubmed-30445462011-03-07 CTX-M β-Lactamase Production and Virulence of Escherichia coli K1 Dubois, Damien Prasadarao, Nemani V. Mittal, Rahul Bret, Laurent Roujou-Gris, Marie Bonnet, Richard Emerg Infect Dis Dispatch We report a patient with neonatal meningitis caused by a CTX-M-1–producing Escherichia coli K1 strain. The influence of CTX-M production on virulence was investigated in cell culture and a newborn mouse model of meningitis. CTX-M production had no influence on virulence but was a major factor in clinical outcome. Centers for Disease Control and Prevention 2009-12 /pmc/articles/PMC3044546/ /pubmed/19961682 http://dx.doi.org/10.3201/eid1512.090928 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Dubois, Damien
Prasadarao, Nemani V.
Mittal, Rahul
Bret, Laurent
Roujou-Gris, Marie
Bonnet, Richard
CTX-M β-Lactamase Production and Virulence of Escherichia coli K1
title CTX-M β-Lactamase Production and Virulence of Escherichia coli K1
title_full CTX-M β-Lactamase Production and Virulence of Escherichia coli K1
title_fullStr CTX-M β-Lactamase Production and Virulence of Escherichia coli K1
title_full_unstemmed CTX-M β-Lactamase Production and Virulence of Escherichia coli K1
title_short CTX-M β-Lactamase Production and Virulence of Escherichia coli K1
title_sort ctx-m β-lactamase production and virulence of escherichia coli k1
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044546/
https://www.ncbi.nlm.nih.gov/pubmed/19961682
http://dx.doi.org/10.3201/eid1512.090928
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