Cargando…

MicroRNA-203 inhibits cell proliferation by repressing ΔNp63 expression in human esophageal squamous cell carcinoma

BACKGROUND: This study was performed to investigate the effect of microRNA-203 (miR-203) and ΔNp63 on cell proliferation and the functional connection between miR-203 and ΔNp63 in ESCC. METHODS: We employed 2 human ESCC cell lines, Eca109 and TE-1, as the model system. The effect of miR-203 and ΔNp6...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Yang, Zeng, Zhi-Yong, Liu, Xiao-Hong, Gong, De-Jun, Tao, Jing, Cheng, He-Zhong, Huang, Sheng-Dong
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044653/ https://www.ncbi.nlm.nih.gov/pubmed/21299870 http://dx.doi.org/10.1186/1471-2407-11-57

Ejemplares similares

Elevated expression of ΔNp63 in advanced esophageal squamous cell carcinoma
por: Kumakura, Yuji, et al.
Publicado: (2017)

ΔNp63α utilizes multiple mechanisms to repress transcription in squamous cell carcinoma cells
por: Gallant-Behm, Corrie L., et al.
Publicado: (2013)

ΔNp63α and microRNAs: leveraging the epithelial-mesenchymal transition
por: Stacy, Andrew J., et al.
Publicado: (2016)

MiR203 mediates subversion of stem cell properties during mammary epithelial differentiation via repression of ΔNP63α and promotes mesenchymal-to-epithelial transition
por: DeCastro, A J, et al.
Publicado: (2013)

E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma
por: Xu, Jing, et al.
Publicado: (2021)

Development of an integrated CRISPRi targeting ΔNp63 for treatment of squamous cell carcinoma
por: Yoshida, Masakazu, et al.
Publicado: (2018)

ΔNp63 Regulates Radioresistance in Human Head and Neck Squamous Carcinoma Cells
por: Sato, Kota, et al.
Publicado: (2023)

DNA Demethylation Switches Oncogenic ΔNp63 to Tumor Suppressive TAp63 in Squamous Cell Carcinoma
por: Pokorna, Zuzana, et al.
Publicado: (2022)

ΔNp63 intronic miR-944 is implicated in the ΔNp63-mediated induction of epidermal differentiation
por: Kim, Kyu-Han, et al.
Publicado: (2015)

Correction: E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma
por: Xu, Jing, et al.
Publicado: (2022)

Bromodomain protein BRDT directs ΔNp63 function and super-enhancer activity in a subset of esophageal squamous cell carcinomas
por: Wang, Xin, et al.
Publicado: (2021)

ΔNp63α transcriptionally represses p53 target genes involved in the radiation-induced DNA damage response: ΔNp63α may cause genomic instability in epithelial stem cells
por: Kudo, Ken-ichi, et al.
Publicado: (2022)

ΔNp63 promotes IGF1 signalling through IRS1 in squamous cell carcinoma
por: Frezza, Valentina, et al.
Publicado: (2018)

ΔNp63 Is Essential for Epidermal Commitment of Embryonic Stem Cells
por: Medawar, Alain, et al.
Publicado: (2008)

ΔNp63 drives epithelial differentiation in glioma
por: Lu, Jia‐Hao, et al.
Publicado: (2020)

YAP Dysregulation by Phosphorylation or ΔNp63-mediated Gene Repression Promotes Proliferation, Survival and Migration in Head and Neck Cancer Subsets
por: Ehsanian, Reza, et al.
Publicado: (2010)

ΔNp63α facilitates proliferation and migration, and modulates the chromatin landscape in intrahepatic cholangiocarcinoma cells
por: Peng, Anghui, et al.
Publicado: (2023)

ΔNp63 in squamous cell carcinoma: defining the oncogenic routes affecting epigenetic landscape and tumour microenvironment
por: Gatti, Veronica, et al.
Publicado: (2019)

Human Papilloma Virus Increases ΔNp63α Expression in Head and Neck Squamous Cell Carcinoma
por: Citro, Simona, et al.
Publicado: (2020)

c-Abl phosphorylation of ΔNp63α is critical for cell viability
por: Yuan, M, et al.
Publicado: (2010)

HuR Is Necessary for Mammary Epithelial Cell Proliferation and Polarity at Least in Part via ΔNp63
por: Yan, Wensheng, et al.
Publicado: (2012)

ΔNp63 silencing, DNA methylation shifts, and epithelial-mesenchymal transition resulted from TAp63 genome editing in squamous cell carcinoma
por: Katoh, Iyoko, et al.
Publicado: (2023)

ΔNp63α modulates histone methyl transferase SETDB1 to transcriptionally repress target genes in cancers
por: Regina, C, et al.
Publicado: (2016)

Targeting of ΔNp63α by miR‐522 promotes the migration of breast epithelial cells
por: Dong, Yuanyuan, et al.
Publicado: (2021)

MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells
por: Riemondy, Kent, et al.
Publicado: (2015)

ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma
por: Cam, Maren, et al.
Publicado: (2016)

ΔNp63α-mediated epigenetic regulation in keratinocyte senescence
por: Kuang, Linghan, et al.
Publicado: (2023)

ΔNp63 activates the Fanconi anemia DNA repair pathway and limits the efficacy of cisplatin treatment in squamous cell carcinoma
por: Bretz, Anne Catherine, et al.
Publicado: (2016)

ΔNp63α promotes Bortezomib resistance via the CYGB–ROS axis in head and neck squamous cell carcinoma
por: Zhou, Peng, et al.
Publicado: (2022)

ING1b-inducible microRNA203 inhibits cell proliferation
por: Chen, J, et al.
Publicado: (2013)

Tumor suppressor WWOX binds to ΔNp63α and sensitizes cancer cells to chemotherapy
por: Salah, Z, et al.
Publicado: (2013)

ΔNp63α Transcriptionally Regulates the Expression of CTEN That Is Associated with Prostate Cell Adhesion
por: Yang, Kuan, et al.
Publicado: (2016)

ΔNp63 regulates the expression of hyaluronic acid-related genes in breast cancer cells
por: Gatti, Veronica, et al.
Publicado: (2018)

ΔNp63α promotes Epstein-Barr virus latency in undifferentiated epithelial cells
por: Van Sciver, Nicholas, et al.
Publicado: (2021)

Prognostic role of ΔNp63 expression in canine transitional cell carcinoma of the urinary bladder
por: Nishimori, Tomohiro, et al.
Publicado: (2021)

Identifying pathways regulating the oncogenic p53 family member ΔNp63 provides therapeutic avenues for squamous cell carcinoma
por: Pokorna, Zuzana, et al.
Publicado: (2022)

Correction to: ΔNp63α promotes Bortezomib resistance via the CYGB–ROS axis in head and neck squamous cell carcinoma
por: Zhou, Peng, et al.
Publicado: (2022)

A Hidden Role of the Inactivated FANCD2: Upregulating ΔNp63
por: Panneerselvam, Jayabal, et al.
Publicado: (2013)

MicroRNA-9 promotes tumor metastasis via repressing E-cadherin in esophageal squamous cell carcinoma
por: Song, Ye, et al.
Publicado: (2014)

ΔNp63 to TAp63 expression ratio as a potential molecular marker for cervical cancer prognosis
por: Park, Sunyoung, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_neeo1gthmaec4as133haktdh55