Responsiveness of genes to manipulation of transcription factors in ES cells is associated with histone modifications and tissue specificity

BACKGROUND: In addition to determining static states of gene expression (high vs. low), it is important to characterize their dynamic status. For example, genes with H3K27me3 chromatin marks are not only suppressed but also poised for activation. However, the responsiveness of genes to perturbations...

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Detalles Bibliográficos
Autores principales: Sharov, Alexei A, Nishiyama, Akira, Piao, Yulan, Correa-Cerro, Lina S, Amano, Tomokazu, Thomas, Marshall, Mehta, Samir, Ko, Minoru SH
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044670/
https://www.ncbi.nlm.nih.gov/pubmed/21306619
http://dx.doi.org/10.1186/1471-2164-12-102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044670/
https://www.ncbi.nlm.nih.gov/pubmed/21306619
http://dx.doi.org/10.1186/1471-2164-12-102

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