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Responsiveness of genes to manipulation of transcription factors in ES cells is associated with histone modifications and tissue specificity
BACKGROUND: In addition to determining static states of gene expression (high vs. low), it is important to characterize their dynamic status. For example, genes with H3K27me3 chromatin marks are not only suppressed but also poised for activation. However, the responsiveness of genes to perturbations...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044670/ https://www.ncbi.nlm.nih.gov/pubmed/21306619 http://dx.doi.org/10.1186/1471-2164-12-102 |