Phosphodiesterase 7 Inhibition Preserves Dopaminergic Neurons in Cellular and Rodent Models of Parkinson Disease

BACKGROUND: Phosphodiesterase 7 plays a major role in down-regulation of protein kinase A activity by hydrolyzing cAMP in many cell types. This cyclic nucleotide plays a key role in signal transduction in a wide variety of cellular responses. In the brain, cAMP has been implicated in learning, memor...

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Detalles Bibliográficos
Autores principales: Morales-Garcia, Jose A., Redondo, Miriam, Alonso-Gil, Sandra, Gil, Carmen, Perez, Concepción, Martinez, Ana, Santos, Angel, Perez-Castillo, Ana
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044733/
https://www.ncbi.nlm.nih.gov/pubmed/21390306
http://dx.doi.org/10.1371/journal.pone.0017240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044733/
https://www.ncbi.nlm.nih.gov/pubmed/21390306
http://dx.doi.org/10.1371/journal.pone.0017240

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