TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort

In a genome-wide association study of frontotemporal lobar degeneration with pathological inclusions of TAR DNA-binding protein, significant association was obtained with three single nucleotide polymorphisms at 7p21.3, in a region encompassing the gene TMEM106B. This study also suggested a potentia...

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Detalles Bibliográficos
Autores principales: van der Zee, Julie, Van Langenhove, Tim, Kleinberger, Gernot, Sleegers, Kristel, Engelborghs, Sebastiaan, Vandenberghe, Rik, Santens, Patrick, Van den Broeck, Marleen, Joris, Geert, Brys, Jolien, Mattheijssens, Maria, Peeters, Karin, Cras, Patrick, De Deyn, Peter P., Cruts, Marc, Van Broeckhoven, Christine
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044834/
https://www.ncbi.nlm.nih.gov/pubmed/21354975
http://dx.doi.org/10.1093/brain/awr007

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