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A Review on Automatic Analysis of Human Embryo Microscope Images
Over the last 30 years the process of in vitro fertilisation (IVF) has evolved considerably, yet the efficiency of this treatment remains relatively poor. The principal challenge faced by doctors and embryologists is the identification of the embryo with the greatest potential for producing a child....
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Formato: | Texto |
Lenguaje: | English |
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Bentham Open
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044885/ https://www.ncbi.nlm.nih.gov/pubmed/21379391 http://dx.doi.org/10.2174/1874120701004010170 |
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author | Filho, E. Santos Noble, J.A Wells, D |
author_facet | Filho, E. Santos Noble, J.A Wells, D |
author_sort | Filho, E. Santos |
collection | PubMed |
description | Over the last 30 years the process of in vitro fertilisation (IVF) has evolved considerably, yet the efficiency of this treatment remains relatively poor. The principal challenge faced by doctors and embryologists is the identification of the embryo with the greatest potential for producing a child. Current methods of embryo viability assessment provide only a rough guide to potential. In order to improve the odds of a successful pregnancy it is typical to transfer more than one embryo to the uterus. However, this often results in multiple pregnancies (twins, triplets, etc), which are associated with significantly elevated risks of serious complications. If embryo viability could be assessed more accurately, it would be possible to transfer fewer embryos without negatively impacting IVF pregnancy rates. In order to assist with the identification of viable embryos, several scoring systems based on morphological criteria have been developed. However, these mostly rely on a subjective visual analysis. Automated assessment of morphological features offers the possibility of more accurate quantification of key embryo characteristics and elimination of inter- and intra-observer variation. In this paper, we describe the main embryo scoring systems currently in use and review related works on embryo image analysis that could lead to an automatic and precise grading of embryo quality. We summarise achievements, discuss challenges ahead, and point to some possible future directions in this research field. |
format | Text |
id | pubmed-3044885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Bentham Open |
record_format | MEDLINE/PubMed |
spelling | pubmed-30448852011-03-04 A Review on Automatic Analysis of Human Embryo Microscope Images Filho, E. Santos Noble, J.A Wells, D Open Biomed Eng J Article Over the last 30 years the process of in vitro fertilisation (IVF) has evolved considerably, yet the efficiency of this treatment remains relatively poor. The principal challenge faced by doctors and embryologists is the identification of the embryo with the greatest potential for producing a child. Current methods of embryo viability assessment provide only a rough guide to potential. In order to improve the odds of a successful pregnancy it is typical to transfer more than one embryo to the uterus. However, this often results in multiple pregnancies (twins, triplets, etc), which are associated with significantly elevated risks of serious complications. If embryo viability could be assessed more accurately, it would be possible to transfer fewer embryos without negatively impacting IVF pregnancy rates. In order to assist with the identification of viable embryos, several scoring systems based on morphological criteria have been developed. However, these mostly rely on a subjective visual analysis. Automated assessment of morphological features offers the possibility of more accurate quantification of key embryo characteristics and elimination of inter- and intra-observer variation. In this paper, we describe the main embryo scoring systems currently in use and review related works on embryo image analysis that could lead to an automatic and precise grading of embryo quality. We summarise achievements, discuss challenges ahead, and point to some possible future directions in this research field. Bentham Open 2010-10-11 /pmc/articles/PMC3044885/ /pubmed/21379391 http://dx.doi.org/10.2174/1874120701004010170 Text en © Filho et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Article Filho, E. Santos Noble, J.A Wells, D A Review on Automatic Analysis of Human Embryo Microscope Images |
title | A Review on Automatic Analysis of Human Embryo Microscope Images |
title_full | A Review on Automatic Analysis of Human Embryo Microscope Images |
title_fullStr | A Review on Automatic Analysis of Human Embryo Microscope Images |
title_full_unstemmed | A Review on Automatic Analysis of Human Embryo Microscope Images |
title_short | A Review on Automatic Analysis of Human Embryo Microscope Images |
title_sort | review on automatic analysis of human embryo microscope images |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044885/ https://www.ncbi.nlm.nih.gov/pubmed/21379391 http://dx.doi.org/10.2174/1874120701004010170 |
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