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Inhibition of angiogenesis and suppression of colorectal cancer metastatic to the liver using the Sleeping Beauty Transposon System

BACKGROUND: Metastatic colon cancer is one of the leading causes of cancer-related death worldwide, with disease progression and metastatic spread being closely associated with angiogenesis. We investigated whether an antiangiogenic gene transfer approach using the Sleeping Beauty (SB) transposon sy...

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Detalles Bibliográficos
Autores principales: Belur, Lalitha R, Podetz-Pedersen, Kelly M, Sorenson, Brent S, Hsu, Alice H, Parker, Josh B, Carlson, Cathy S, Saltzman, Daniel A, Ramakrishnan, S, McIvor, R Scott
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045363/
https://www.ncbi.nlm.nih.gov/pubmed/21310067
http://dx.doi.org/10.1186/1476-4598-10-14