Cargando…
Behavioral Characterization of a Mouse Model Overexpressing DSCR1/ RCAN1
DSCR1/ RCAN1 is a chromosome 21 gene found to be overexpressed in the brains of Down syndrome (DS) and postulated as a good candidate to contribute to mental disability. However, even though Rcan1 knockout mice have pronounced spatial learning and memory deficits, the possible deleterious effects of...
Autores principales: | Dierssen, Mara, Arqué, Gloria, McDonald, Jerome, Andreu, Nuria, Martínez-Cué, Carmen, Flórez, Jesús, Fillat, Cristina |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045383/ https://www.ncbi.nlm.nih.gov/pubmed/21364922 http://dx.doi.org/10.1371/journal.pone.0017010 |
Ejemplares similares
-
Dyrk1A Is Dynamically Expressed on Subsets of Motor Neurons and in the Neuromuscular Junction: Possible Role in Down Syndrome
por: Arque, Gloria, et al.
Publicado: (2013) -
Overexpression of DSCR1 prevents proliferation and predicts favorable prognosis in colorectal cancer patients
por: Li, Wen-Xiang, et al.
Publicado: (2021) -
Division of labor in the growth cone by DSCR1
por: Catlett, Timothy S., et al.
Publicado: (2016) -
RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis
por: Sun, Xiulian, et al.
Publicado: (2014) -
Spatiotemporal expression of RCAN1 and its isoform RCAN1-4 in the mouse hippocampus after pilocarpine-induced status epilepticus
por: Cho, Kyung-Ok, et al.
Publicado: (2020)