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Thermal- and Oxidative Stress Causes Enhanced Release of NKG2D Ligand-Bearing Immunosuppressive Exosomes in Leukemia/Lymphoma T and B Cells

Immune evasion from NK surveillance related to inadequate NK-cell function has been suggested as an explanation of the high incidence of relapse and fatal outcome of many blood malignancies. In this report we have used Jurkat and Raji cell lines as a model for studies of the NKG2D receptor-ligand sy...

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Detalles Bibliográficos
Autores principales: Hedlund, Malin, Nagaeva, Olga, Kargl, Dominic, Baranov, Vladimir, Mincheva-Nilsson, Lucia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045385/
https://www.ncbi.nlm.nih.gov/pubmed/21364924
http://dx.doi.org/10.1371/journal.pone.0016899