Genome-Wide Association Study Identifies Single Nucleotide Polymorphism in DYRK1A Associated with Replication of HIV-1 in Monocyte-Derived Macrophages

BACKGROUND: HIV-1 infected macrophages play an important role in rendering resting T cells permissive for infection, in spreading HIV-1 to T cells, and in the pathogenesis of AIDS dementia. During highly active anti-retroviral treatment (HAART), macrophages keep producing virus because tissue penetr...

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Detalles Bibliográficos
Autores principales: Bol, Sebastiaan M., Moerland, Perry D., Limou, Sophie, van Remmerden, Yvonne, Coulonges, Cédric, van Manen, Daniëlle, Herbeck, Joshua T., Fellay, Jacques, Sieberer, Margit, Sietzema, Jantine G., van 't Slot, Ruben, Martinson, Jeremy, Zagury, Jean-François, Schuitemaker, Hanneke, van 't Wout, Angélique B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045405/
https://www.ncbi.nlm.nih.gov/pubmed/21364930
http://dx.doi.org/10.1371/journal.pone.0017190

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