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Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice
RATIONALE: By enhancing brain anandamide tone, inhibitors of fatty acid amide hydrolase (FAAH) induce anxiolytic-like effects in rodents and enhance brain serotonergic transmission. Mice lacking the faah gene (FAAH(−/−)) show higher anandamide levels. However, their emotional phenotype is still deba...
Autores principales: | Cassano, Tommaso, Gaetani, Silvana, Macheda, Teresa, Laconca, Leonardo, Romano, Adele, Morgese, Maria Grazia, Cimmino, Concetta Stefania, Chiarotti, Flavia, Bambico, Francis R., Gobbi, Gabriella, Cuomo, Vincenzo, Piomelli, Daniele |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045513/ https://www.ncbi.nlm.nih.gov/pubmed/21042794 http://dx.doi.org/10.1007/s00213-010-2051-0 |
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