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Microhomology-mediated deletion and gene conversion in African trypanosomes

Antigenic variation in African trypanosomes is induced by DNA double-strand breaks (DSBs). In these protozoan parasites, DSB repair (DSBR) is dominated by homologous recombination (HR) and microhomology-mediated end joining (MMEJ), while non-homologous end joining (NHEJ) has not been reported. To fa...

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Detalles Bibliográficos
Autores principales: Glover, Lucy, Jun, Junho, Horn, David
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045614/
https://www.ncbi.nlm.nih.gov/pubmed/20965968
http://dx.doi.org/10.1093/nar/gkq981

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