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Microhomology-mediated deletion and gene conversion in African trypanosomes

Antigenic variation in African trypanosomes is induced by DNA double-strand breaks (DSBs). In these protozoan parasites, DSB repair (DSBR) is dominated by homologous recombination (HR) and microhomology-mediated end joining (MMEJ), while non-homologous end joining (NHEJ) has not been reported. To fa...

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Detalles Bibliográficos
Autores principales:	Glover, Lucy, Jun, Junho, Horn, David
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045614/ https://www.ncbi.nlm.nih.gov/pubmed/20965968 http://dx.doi.org/10.1093/nar/gkq981

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