Expression of Pleiotrophin in the Prostate is Androgen Regulated and it Functions as an Autocrine Regulator of Mesenchyme and Cancer Associated Fibroblasts and as a Paracrine Regulator of Epithelia

BACKGROUND: Androgens and paracrine signaling from mesenchyme/stroma regulate development and disease of the prostate, and gene profiling studies of inductive prostate mesenchyme have identified candidate molecules such as pleiotrophin (Ptn). METHODS: Ptn transcripts and protein were localized by in...

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Detalles Bibliográficos
Autores principales: Orr, Brigid, Vanpoucke, Griet, Grace, O Cathal, Smith, Lee, Anderson, Richard A, Riddick, Antony CP, Franco, Omar E, Hayward, Simon W, Thomson, Axel A
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045659/
https://www.ncbi.nlm.nih.gov/pubmed/20812209
http://dx.doi.org/10.1002/pros.21244

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