Cargando…

Rebamipide, a mucoprotective drug, inhibits NSAIDs-induced gastric mucosal injury: possible involvement of the downregulation of 15-hydroxyprostaglandin dehydrogenase

Prostaglandin E(2) plays an important role in the maintenance of gastric mucosal integrity. The level of biologically active prostaglandin E(2) in the tissue is regulated by the balanced expression of its synthetic enzymes, such as cyclooxygenase, and its catabolic enzyme, 15-hydroxyprostaglandin de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tanigawa, Tetsuya, Watanabe, Toshio, Ohkawa, Fumikazu, Nadatani, Yuji, Otani, Koji, Machida, Hirohisa, Okazaki, Hirotoshi, Yamagami, Hirokazu, Watanabe, Kenji, Tominaga, Kazunari, Fujiwara, Yasuhiro, Takeuchi, Koji, Arakawa, Tetsuo
Formato:	Texto
Lenguaje:	English
Publicado:	the Society for Free Radical Research Japan 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045688/ https://www.ncbi.nlm.nih.gov/pubmed/21373268 http://dx.doi.org/10.3164/jcbn.10-75

Ejemplares similares

Mitochondrial disorders in NSAIDs-induced small bowel injury
por: Watanabe, Toshio, et al.
Publicado: (2011)

Colchicine prevents NSAID-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome
por: Otani, Koji, et al.
Publicado: (2016)

High-Mobility Group Box 1 Inhibits Gastric Ulcer Healing through Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products
por: Nadatani, Yuji, et al.
Publicado: (2013)

Bile Acids Induce Cdx2 Expression Through the Farnesoid X Receptor in Gastric Epithelial Cells
por: Xu, Yingji, et al.
Publicado: (2010)

Lansoprazole, a Proton Pump Inhibitor, Suppresses Production of Tumor Necrosis Factor-α and Interleukin-1β Induced by Lipopolysaccharide and Helicobacter Pylori Bacterial Components in Human Monocytic Cells via Inhibition of Activation of Nuclear Factor-κB and Extracellular Signal-Regulated Kinase
por: Tanigawa, Tetsuya, et al.
Publicado: (2009)

Toll-Like Receptor 2 Mediates Ischemia-Reperfusion Injury of the Small Intestine in Adult Mice
por: Watanabe, Toshio, et al.
Publicado: (2014)

Double-balloon endoscopy WAS effective in diagnosing small intestinal duplication: a case report
por: Nadatani, Yuji, et al.
Publicado: (2016)

Usefulness of Non-Magnifying Narrow-Band Imaging in Screening of Early Esophageal Squamous Cell Carcinoma: A Prospective Comparative Study Using Propensity Score Matching
por: Nagami, Yasuaki, et al.
Publicado: (2014)

NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis
por: Itani, Shigehiro, et al.
Publicado: (2016)

Clinical Efficacy of Endoscopic Submucosal Dissection for Adenocarcinomas of the Esophagogastric Junction
por: Nagami, Yasuaki, et al.
Publicado: (2014)

Gastroduodenal Mucosal Injury in Patients Taking Low-Dose Aspirin and the Role of Gastric Mucoprotective Drugs: Possible Effect of Rebamipide
por: Yamamoto, Takatsugu, et al.
Publicado: (2010)

Postprandial Symptoms Felt at the Lower Part of the Epigastrium and a Possible Association of Pancreatic Exocrine Dysfunction with the Pathogenesis of Functional Dyspepsia
por: Fujikawa, Yoshiko, et al.
Publicado: (2017)

Determination of the adequate dosage of rebamipide, a gastric mucoprotective drug, to prevent low-dose aspirin-induced gastrointestinal mucosal injury
por: Ota, Kazuhiro, et al.
Publicado: (2016)

Sleep disturbances in Japanese patients with inflammatory bowel disease and their impact on disease flare
por: Uemura, Risa, et al.
Publicado: (2016)

Acid Reflux Directly Causes Sleep Disturbances in Rat with Chronic Esophagitis
por: Nakahara, Kenichi, et al.
Publicado: (2014)

Rebamipide ameliorates indomethacin-induced small intestinal damage and proton pump inhibitor-induced exacerbation of this damage by modulation of small intestinal microbiota
por: Tanigawa, Tetsuya, et al.
Publicado: (2021)

Mesenchymal stem cells administered in the early phase of tumorigenesis inhibit colorectal tumor development in rats
por: Katsuno, Takayuki, et al.
Publicado: (2013)

Disorder of autonomic nervous system and its vulnerability to external stimulation in functional dyspepsia
por: Tominaga, Kazunari, et al.
Publicado: (2016)

Microbiome and intestinal ischemia/reperfusion injury
por: Nadatani, Yuji, et al.
Publicado: (2018)

Long-Term Benefits of Smoking Cessation on Gastroesophageal Reflux Disease and Health-Related Quality of Life
por: Kohata, Yukie, et al.
Publicado: (2016)

Correction: Long-Term Benefits of Smoking Cessation on Gastroesophageal Reflux Disease and Health-Related Quality of Life
por: Kohata, Yukie, et al.
Publicado: (2016)

High-fat diet-mediated dysbiosis exacerbates NSAID-induced small intestinal damage through the induction of interleukin-17A
por: Sugimura, Naoki, et al.
Publicado: (2019)

Neutrophil-to-Lymphocyte Ratio for Predicting Loss of Response to Infliximab in Ulcerative Colitis
por: Nishida, Yu, et al.
Publicado: (2017)

Hybrid therapy with locoregional steroid injection and polyglycolic acid sheets to prevent stricture after esophageal endoscopic submucosal dissection
por: Nagami, Yasuaki, et al.
Publicado: (2016)

Analysis of the Risk Factors of Surgery after Endoscopic Balloon Dilation for Small Intestinal Strictures in Crohn's Disease Using Double-balloon Endoscopy
por: Nishida, Yu, et al.
Publicado: (2017)

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of High-Dose Rebamipide Treatment for Low-Dose Aspirin-Induced Moderate-to-Severe Small Intestinal Damage
por: Watanabe, Toshio, et al.
Publicado: (2015)

Preventive effect of rebamipide on NSAID-induced lower gastrointestinal tract injury using FAERS and JADER
por: Imai, Toru, et al.
Publicado: (2022)

A Metastatic Gastric Tumor from Ovarian Cancer
por: Kono, Mitsuhiro, et al.
Publicado: (2017)

Single Locoregional Triamcinolone Injection Immediately After Esophageal Endoscopic Submucosal Dissection Prevents Stricture Formation
por: Nagami, Yasuaki, et al.
Publicado: (2017)

Does discontinuation of antithrombotics affect the diagnostic yield of small bowel capsule endoscopy in patients demonstrating obscure gastrointestinal bleeding?
por: Nakamura, Shiro, et al.
Publicado: (2018)

The Traditional Japanese Medicine Rikkunshito Promotes Gastric Emptying via the Antagonistic Action of the 5-HT(3) Receptor Pathway in Rats
por: Tominaga, K., et al.
Publicado: (2011)

Association between endoscopic findings of eosinophilic esophagitis and responsiveness to proton pump inhibitors
por: Sawada, Akinari, et al.
Publicado: (2019)

Involvement of gliadin, a component of wheat gluten, in increased intestinal permeability leading to non-steroidal anti-inflammatory drug-induced small-intestinal damage
por: Shimada, Sunao, et al.
Publicado: (2019)

Gastric acid inhibitor aggravates indomethacin-induced small intestinal injury via reducing Lactobacillus johnsonii
por: Nadatani, Yuji, et al.
Publicado: (2019)

Small Bowel Endoscopy in Inflammatory Bowel Disease
por: Yamagami, Hirokazu, et al.
Publicado: (2013)

Slco2a1 deficiency exacerbates experimental colitis via inflammasome activation in macrophages: a possible mechanism of chronic enteropathy associated with SLCO2A1 gene
por: Nakata, Rieko, et al.
Publicado: (2020)

Comparison of Prevention of NSAID-Induced Gastrointestinal Complications by Rebamipide and Misoprostol: A Randomized, Multicenter, Controlled Trial—STORM STUDY
por: Park, Soo-Heon, et al.
Publicado: (2007)

Mucoprotective effect of ellagic acid in 5 fluorouracil-induced intestinal mucositis model
por: AL-hoshary, Dareen Mahmood, et al.
Publicado: (2023)

Rebamipide and mosapride enhance pilocarpine-induced salivation
por: Urita, Yoshihisa, et al.
Publicado: (2009)

Association between Functional Dyspepsia and Gastric Depressive Erosions in Japanese Subjects
por: Tanaka, Fumio, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_mmkcasclv7a9cnm0dp0jipvi16