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Spatiotemporal regulations of Wee1 at the G2/M transition

Wee1 is a protein kinase that negatively regulates mitotic entry in G2 phase by suppressing cyclin B–Cdc2 activity, but its spatiotemporal regulations remain to be elucidated. We observe the dynamic behavior of Wee1 in Schizosaccharomyces pombe cells and manipulate its localization and kinase activi...

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Detalles Bibliográficos
Autores principales: Masuda, Hirohisa, Fong, Chii Shyang, Ohtsuki, Chizuru, Haraguchi, Tokuko, Hiraoka, Yasushi
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046054/
https://www.ncbi.nlm.nih.gov/pubmed/21233285
http://dx.doi.org/10.1091/mbc.E10-07-0644